4 Meses

ARNAO, M. B. et al. The Potential of Phytomelatonin as a Nutraceutical. Molecules, v. 23, 238, 2018. AULD, Fiona et al. Evidence for the efficacy of melatonin in the treatment of primary adult sleep disorders. p. 10–22, 2017. BESAG, F. M. C. et al. Adverse Events Associated with Melatonin for the Treatment of Primary or Secondary Sleep Disorders: A Systematic Review. CNS Drugs, 2019. BAKALOV, D. et al. Commentary regarding “neuroactive compounds in foods: Occurrence, mechanism and potential health effects”. Food Research International, v. 132, 2020. BONOMINI, F. et al. Dietary Melatonin Supplementation Could be a Promising Preventing/Therapeutic Approach for a Variety of Liver Diseases. Nutrients, v. 10, 1135, 2018. BRZEZINSKI, Amnon et al. Effects of exogenous melatonin on sleep: A meta-analysis. Sleep Medicine Reviews, v. 9, n. 1, p. 41–50, 2005. BUSCEMI, Nina et al. The efficacy and safety of exogenous melatonin for primary sleep disorders: A meta-analysis. Journal of General Internal Medicine. [S.l: s.n.]. Disponível em: . Acesso em: 8 dez. 2019, 2005. BUSCEMI, Nina et al. Efficacy and safety of exogenous melatonin for secondary sleep disorders and sleep disorders accompanying sleep restriction: Meta-analysis. British Medical Journal. [S.l: s.n.]. Disponível em: . Acesso em: 8 dez. 2019., 2006. CHAUDHRY, Simriti K.; SUSSER, Leah C. Considerations in Treating Insomnia During Pregnancy: A Literature Review. Psychosomatics. [S.l: s.n.]., 2018. CHEUNG, F. et al. Preclinical evaluation of pharmacokinetics and safety of melatonin in propylene glycol for intravenous administration. Journal of Pineal Research, v. 41, n. 4, p. 337 – 343, 2006. Dawson, D. D. et al. Effect of sustained nocturnal transbucal melatonin administration on sleep and temperature in elderly insomniacs. Journal of Biological Rhythms, v. 13, n. 6, p. 532 – 538, 1998. EMA, European Medicine Agency. Assessment Report for Circadin. Procedure nº EMEA/H/C/695, 2007. EMA, European Medicine Agency. Circadin (melatonin). Procedure nº: EMA/H/C/695/P46/019 Marketing authorisation holder (MAH): RAD Neurim Pharmaceuticals EEC Ltd. CHMP 99 assessment report for paediatric use studies submitted according to Article 46 of the Regulation (EC) Nº 1901/2006, 2015. FERRACIOLO-ODA, Eduardo; QAWASMI, Ahmad; BLOCH, Michael H. Meta-Analysis: Melatonin for the Treatment of Primary Sleep Disorders. PLOS ON, v. 8, n. 5, p. 1–6, 2013. FERREIRA, C. S. et al. Melatonina: Modulador de Morte Celular. Rev. Assoc. Med. Bras., 2010; 56 (6): 715 – 8. FERREIRA, R. F. D. F. Análise da dinâmica da melatonina liquórica. Dissertação apresentada ao Programa de Pós-Graduação em Fisiologia e Biofísica do Instituto de Ciências Biomédicas da Universidade de São Paulo. [Dissertação de Mestrado]. 2010. FORSLING, Mary L.; WHEELER, M. J.; WILLIAMS, A. J. The effect of melatonin administration on pituitary hormone secretion in man. Clinical Endocrinology, 1999. FORSLING, Mary L.; WHEELER, M. J.; WILLIAMS, A. J. The effect of melatonin administration on pituitary hormone secretion in man. Clinical Endocrinology, 1999. GOMES, F. C. Caracterização do mercado português de suplementos alimentares em 2014. Dissertação para a obtenção do Grau de Mestre em Engenharia Alimentar. Universidade de Lisboa, 2014. HERXHEIMER, Andrew; PETRIE, Keith J. Melatonin for the prevention and treatment of jet lag. Cochrane Database of Systematic Reviews, 2002. JAHNKE, G. et al. Maternal and Developmental Toxicity Evaluation of Melatonin Administered Orally to Pregnant Sprague-Dawley Rats. Toxicological Sciences, n. 50, p. 271 -279, 1999. LI, T. et al. Exogenous melatonin as a treatment for secondary sleep disorders: A systematic review and meta-analysis. Frontiers in Neuroendocrinology. [S.l: s.n.]., 2019. LIIRA, J. et al. Pharmacological interventions for sleepiness and sleep disturbances caused by shift work. Cochrane Database of Systematic Reviews. [S.l: s.n.], 2014. LIU, J. et al. Melatonin increases reactive aggression in humans. Psychopharmacology, v. 234, n. 19, p. 2971 – 2978, 2017. LUBOSHITZKY, Rafael et al. Melatonin administration alters Semen quality in healthy men. Journal of Andrology, 2002. MENDES, C. Adaptações do animal idoso ao exercício físico: papel da suplementação diária com melatonina. Dissertação apresentada ao Programa de Pós-Graduação em Fisiologia Humana do Instituto de Ciências Biomédicas da Universidade de São Paulo, para obtenção do título de mestre. São Paulo, 2012. 100 MENG, X. et al. Dietary Sources and Bioactivities of Melatonin. Nutrients, v. 9, p. 1 – 64, 2017. MILAGRES, M. P. et al. Night milking adds value to cow’s milk. J Sci Food Agric, v. 94, p. 1.688 – 1.692, 2014. MUNDEY K., et al. Phasedependent treatment of delayed sleep phase syndrome with melatonin. Sleep, v. 28, p. 1271-8, 2005. NAIR, A. B.; Jacob S. A simple practice guide for dose conversion between animals and human. J Basic Clin Pharma, v. 7, n. 7, p. 27-31, 2016. NINOMIYA, T. et al. Effects of exogenous melatonin on pituitary hormones in humans. Clinical Physiology, 2001. OKATANI, Yuji; SAGARA, Yusuke. Role of melatonin in nocturnal prolactin secretion in women with normoprolactinemia and mild hyperprolactinemia. American Journal of Obstetrics and Gynecology, 1993. PREVO, M. et al. Twenty-Eight-Day Toxicity Study of Melatonin Infused Subcutaneously in Rats Via an Osmotic Pump. International Journal of Toxicology, n. 19, p. 107 – 118, 2000. REITER, R. J. Melatonin: Clinical Relevance. Best Practice & Research Clinical Endocrinology and Metabolism, v. 17, n. 2, p. 273 – 285, 2003. ROMANINI, E. B. Fontes de variação da concentração de melatonina no leite. Dissertação apresentada à UNOPAR como requisito parcial para a obtenção do título de Mestre em Ciência e Tecnologia do Leite e Derivados. Londrina, 2017. SEABRA, M. L. V. et al. Randomized, double-blind clinical trial, controlled with placebo, of the toxicology of chronic melatonin treatment. Journal of Pineal Research, v. 29, n. 4, p. 193–200, 2000. SHIZARI, A. et al. A Radiological review on melatonina: a novel radioprotector. Journal of radiation research, v. 48, n. 4, p. 263 – 272, 2007. SINGH, H. J. et al. Effect of melatonin supplementation on pregnancy outcome in Wistar-Kyoto and Sprague-Dawley rats. Sheng li xue bao : [Acta physiologica Sinica], 2013. SOUSA NETO J. A., CASTRO B. F. Melatonina, ritmos biológicos e sono – uma revisão de literatura. Rev Bras Neurol, v. 44, n. 1, p. 5 – 11, 2008. SUGDEN, D. Psychopharmacological effects of melatonin in mouse and rat. Journal of Pharmacology and Experimental Therapeutics, 1983.

Melatonina 0,21 mg Solução oral para Melatonina 0,05 ml QSP 30 ml

Usar 1 gota via oral ao dia

Melatonina Solução Oral com 0,21 mg por Gota. "Não existe comprovação que este suplemento trate ou cure doenças"